Two new approaches promise to facilitate the identification of zinc fingers that function optimally in vivo.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Miller, J., McLachlan, A.D. & Klug, A. EMBO J. 4, 1609–1614 (1985).
Blancafort, P., Magnenat, L. & Barbas, C.F. Nat. Biotechnol. 21, 269–274 (2003).
Bae, K.H. et al. Nat. Biotechnol. 21, 275–280 (2003).
Pavletich, N.P. & Pabo, C.O. Science 252, 809–817 (1991).
Desjarlais, J.R. & Berg, J.M. Proc. Natl. Acad. Sci. USA 89, 7345–7349 (1992).
Ansari, A.Z. & Mapp, A.K. Curr. Opin. Chem. Biol. 6, 765–772 (2002).
Beerli, R.R. & Barbas, C.F. Nat. Biotechnol. 20, 135–141 (2002).
Friesen, W.J & Darby, M.K. Nat. Struct. Biol. 5, 543–546 (1998).
Liu, P.Q. et al. J. Biol. Chem. 276, 11323–11334 (2001).
Cheng, X., Boyer, J.L. & Juliano, R.L. Proc. Natl. Acad. Sci. USA. 94, 14120–14125 (1994).
Cartegni, L. & Krainer, A.R. Nat. Struct. Biol. 10, 120–125 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ansari, A. Fingers reach for the genome. Nat Biotechnol 21, 242–243 (2003). https://doi.org/10.1038/nbt0303-242
Issue Date:
DOI: https://doi.org/10.1038/nbt0303-242