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Knocking out xenograft rejection

Two reports on the knockout of one allele of the α1,3-galactosyltransferase gene in pigs bring us one step closer to the transplantation of pig organs into people.

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Figure 1: α1,3Gal in the fate of xenografts and the mechanisms of tissue injury.

© Bob Crimi

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Platt, J. Knocking out xenograft rejection. Nat Biotechnol 20, 231–232 (2002). https://doi.org/10.1038/nbt0302-231

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