Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Systematic tracking of cell fate changes

High-throughput measurements across several regulatory levels provide a comprehensive view of ES-cell differentiation.

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Systematic monitoring of differentiating ES cells.

References

  1. Lu, R. et al. Nature 462, 358–362 (2009).

    Article  CAS  Google Scholar 

  2. MacArthur, B.D., Ma'ayan, A. & Lemischka, I.R. Cold Spring Harb. Symp. Quant. Biol. 73, 211–215 (2008).

    Article  CAS  Google Scholar 

  3. Mitsui, K. et al. Cell 113, 631–642 (2003).

    Article  CAS  Google Scholar 

  4. Chambers, I. et al. Cell 113, 643–655 (2003).

    Article  CAS  Google Scholar 

  5. de Sousa Abreu, R., Penalva, L.O., Marcotte, E.M. & Vogel, C. Mol. Biosyst. 5, 1512–1526 (2009).

    PubMed  Google Scholar 

  6. MacArthur, B.D., Lachmann, A., Lemischka, I.R. & Ma'ayan, A. Bioinformatics 26, 143–144 (2010).

    Article  CAS  Google Scholar 

  7. Marson, A. et al. Cell 134, 521–533 (2008).

    Article  CAS  Google Scholar 

  8. Singh, A.M., Hamazaki, T., Hankowski, K.E. & Terada, N. Stem Cells 25, 2534–2542 (2007).

    Article  CAS  Google Scholar 

  9. Chambers, I. et al. Nature 450, 1230–1234 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Stuart H Orkin.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Kim, J., Orkin, S. Systematic tracking of cell fate changes. Nat Biotechnol 28, 146–147 (2010). https://doi.org/10.1038/nbt0210-146

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt0210-146

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing