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Putting the lid on phosphodiesterase 4

Nature Biotechnology volume 28, pages38–40(2010)Cite this article

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Structural insights into the regulation of phosphodiesterase 4 lead to the discovery of allosteric modulators with reduced side effects.

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Figure 1: Structural basis of PDE4 regulation.

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Author information

Affiliations

  1. Miles D. Houslay is in the Department of Neuroscience and Molecular Pharmacology, University of Glasgow, Glasgow, G12 8QQ, Scotland, UK

    Miles D Houslay

  2. David R. Adams is in the Department of Chemistry, Heriot-Watt University, Edinburgh EH14 4AS, Scotland, UK.

    David R Adams

Authors
  1. Miles D Houslay
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  2. David R Adams
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Correspondence to Miles D Houslay.

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Houslay, M., Adams, D. Putting the lid on phosphodiesterase 4. Nat Biotechnol 28, 38–40 (2010). https://doi.org/10.1038/nbt0110-38

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