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Animal cloning and the FDA—the risk assessment paradigm under public scrutiny

The evidence gathered thus far—ultimately to be published in the Draft Risk Assessment on Animal Cloning—indicates that there are no unique risks associated with animal cloning.

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References

  1. National Academy of Sciences, National Research Council. Animal Biotechnology: Science-Based Concerns (National Academies Press, Washington, DC, 2002).

  2. Wilmut, I., Schnieke, A.E., McWhir, J., Kind, A.J. & Campbell, K.H. Nature 385, 810–813 (1997).

    CAS  Article  PubMed  Google Scholar 

  3. Prather, R.S. et al. Biol. Reprod. 37, 859–866 (1987).

    CAS  Article  PubMed  Google Scholar 

  4. Cibelli, J.B. et al. Science 280, 1256–1258 (1998).

    CAS  Article  PubMed  Google Scholar 

  5. Jones, P.A. & Takai, D. Science 293, 1068–1070 (2001).

    CAS  Article  PubMed  Google Scholar 

  6. Jaenisch, R. & Bird, A. Nat. Genet. 33 Suppl., 245–254 (2003).

    CAS  Article  PubMed  Google Scholar 

  7. Cezar, G.G. Cloning Stem Cells 5, 165–180 (2003).

    CAS  Article  PubMed  Google Scholar 

  8. Bourc'his, D. et al. Curr. Biol. 11, 1542–1546 (2001).

    CAS  Article  PubMed  Google Scholar 

  9. Dean, W. et al. Proc. Natl. Acad. Sci. USA 8, 13734–13738 (2001).

    Article  Google Scholar 

  10. Kang, Y.K. et al. Nat. Genet. 28, 173–177 (2001).

    CAS  Article  PubMed  Google Scholar 

  11. Kang, Y.K. et al. FEBS Lett. 99, 55–58 (2001).

    Article  Google Scholar 

  12. Kang, Y.K. et al. EMBO J. 21, 1092–1100 (2002).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  13. Ohgane, J. et al. Genesis 30, 45–50 (2001).

    CAS  Article  PubMed  Google Scholar 

  14. Wilmut, I. Nat. Med. 8, 215–216 (2002).

    CAS  Article  PubMed  Google Scholar 

  15. Santos, F. et al. Curr. Biol. 13, 1116–1121 (2003).

    CAS  Article  PubMed  Google Scholar 

  16. Shi, W., Dirim, F., Wolf, E., Zakhartchenko, V. & Haaf, T. Biol. Reprod. 71, 340–347 (2004).

    CAS  Article  PubMed  Google Scholar 

  17. Chen, T. et al. Front. Biosci. 10, 3002–3008 (2005).

    CAS  Article  PubMed  Google Scholar 

  18. Yamazaki, Y. et al. Proc. Natl. Acad. Sci.USA 100, 12207–12212 (2003).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  19. Chavatte-Palmer, P. et al. Biol. Reprod. 66, 1596–1603 (2002).

    CAS  Article  PubMed  Google Scholar 

  20. Surani, M.A. Nature 414, 122–128 (2001).

    CAS  Article  PubMed  Google Scholar 

  21. Yamazaki, Y. et al. Proc. Natl. Acad. Sci. USA 102, 11361–11366 (2005).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  22. Avner, P. & Heard, E. Nat. Rev. Genet. 2, 59–67 (2001).

    CAS  Article  PubMed  Google Scholar 

  23. Heard, E. Curr. Opin. Genet. Dev. 15, 482–489 (2005).

    CAS  Article  PubMed  Google Scholar 

  24. Gauthier, M. et al. Cloning Stem Cells 3, 151–155 (2001).

    CAS  Article  PubMed  Google Scholar 

  25. Enright, B.P. et al. Biol. Reprod. 66, 291–296 (2002).

    CAS  Article  PubMed  Google Scholar 

  26. Pace, M.M. et al. Biol. Reprod. 67, 334–339 (2002).

    CAS  Article  PubMed  Google Scholar 

  27. Heyman, Y. et al. Cloning Stem Cells 6, 111–120 (2004).

    CAS  Article  PubMed  Google Scholar 

  28. Martin, M., Adams, C. & Wiseman, B. Theriogenology 62, 113–122 (2004).

    CAS  Article  PubMed  Google Scholar 

  29. Wells, D.N. Cloning Stem Cells 6, 101–110 (2004).

    CAS  Article  PubMed  Google Scholar 

  30. Shiga, K. et al. Theriogenology 64, 334–343 (2005).

    Article  PubMed  Google Scholar 

  31. Tecirlioglu, R.T. et al. Theriogenology 65 1783–1799 (2005).

    Article  PubMed  Google Scholar 

  32. Walker, S.C. et al. Theriogenology 67: 178–184 (2007)

    CAS  Article  PubMed  Google Scholar 

  33. Mir, B., Zaunbrecher, G., Archer, G.S., Friend, T.H. & Piedrahita, J.A. Cloning Stem Cells 7, 119–125 (2005).

    CAS  Article  PubMed  Google Scholar 

  34. Rudenko, L., Matheson, J.C., Adams, A.L., Dubbin, E.S. & Greenlees, K.J. Cloning Stem Cells 6, 79–93 (2004).

    CAS  Article  PubMed  Google Scholar 

  35. Hill, A.B. Proc. R. Soc. Med. 58, 295–300 (1965).

    CAS  PubMed  PubMed Central  Google Scholar 

  36. Tian, X.C. et al. Proc. Natl. Acad. Sci. USA 102, 6261–6266 (2005).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  37. Walsh, M.K., Lucey, J.A., Govindasamy-Lucey, S., Pace, M.M. & Bishop, M.D. Cloning Stem Cells 5, 213–219 (2003).

    CAS  Article  PubMed  Google Scholar 

  38. International Food Information Council. IFIC Survey: Food Biotechnology Not A Top-Of-Mind Concern for American Consumers (2005). <http://www.ific.org/research/upload/2005BiotechSurvey.pdf>

  39. Pew Initiative on Food and Biotechnology. Public Sentiment about Genetically Modified Food (Pew Initiative on Food and Biotechnology, Washington, DC, 2005).

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Rudenko, L., Matheson, J. & Sundlof, S. Animal cloning and the FDA—the risk assessment paradigm under public scrutiny. Nat Biotechnol 25, 39–43 (2007). https://doi.org/10.1038/nbt0107-39

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  • DOI: https://doi.org/10.1038/nbt0107-39

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