Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

The myriad targets of a T cell

Nature Biotechnology volume 36, pages 1152–1154 (2018)Cite this article

Subjects

Two methods for measuring cross-reactivity could boost the safety of T-cell therapies.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Two methods for assessing T cell–pMHC binding patterns.

References

  1. Sewell, A.K. Nat. Rev. Immunol. 12, 669–677 (2012).

    Article  CAS  Google Scholar 

  2. Birnbaum, M.E. et al. Cell 157, 1073–1087 (2014).

    Article  CAS  Google Scholar 

  3. Zhang, S. et al. Nat. Biotechnol. 36, 1156–1159 (2018).

    Article  CAS  Google Scholar 

  4. Bentzen, A.K. et al. Nat. Biotechnol. 36, 1191–1196 (2018).

    Article  CAS  Google Scholar 

  5. Altman, J.D. et al. Science 274, 94–96 (1996).

    Article  CAS  Google Scholar 

  6. Newell, E.W. et al. Nat. Biotechnol. 31, 623–629 (2013).

    Article  CAS  Google Scholar 

  7. Huang, J. et al. Proc. Natl. Acad. Sci. USA 113, E1890–E1897 (2016).

    Article  CAS  Google Scholar 

  8. Dolton, G. et al. Front. Immunol. 9, 1378 (2018).

    Article  Google Scholar 

  9. Bentzen, A.K. et al. Nat. Biotechnol. 34, 1037–1045 (2016).

    Article  CAS  Google Scholar 

  10. Rodenko, B. et al. Nat. Protoc. 1, 1120–1132 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Aswin Natarajan and Michelle Krogsgaard are in the Department of Pathology and Perlmutter Cancer Center, New York University School of Medicine, New York, New York, USA.,

    Aswin Natarajan & Michelle Krogsgaard

Authors
  1. Aswin Natarajan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Michelle Krogsgaard
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Michelle Krogsgaard.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Natarajan, A., Krogsgaard, M. The myriad targets of a T cell. Nat Biotechnol 36, 1152–1154 (2018). https://doi.org/10.1038/nbt.4309

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt.4309

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research