Supplementary Figure 2: Specific hsiRNA-mediated downregulation of sFLT1 mRNA isoforms in human placental cytotrophoblast (CTB). | Nature Biotechnology

Supplementary Figure 2: Specific hsiRNA-mediated downregulation of sFLT1 mRNA isoforms in human placental cytotrophoblast (CTB).

From: RNAi modulation of placental sFLT1 for the treatment of preeclampsia

Supplementary Figure 2

a) Dose-response curves of hsiRNAPPIB silencing of PPIB mRNA in CTB (n=3 biologically independent experiments, mean +SD). b) Dose-response curves of hsiRNAsFLT1-2283 and hsiRNAsFLT1-2519 silencing of sFLT1-i13 and sFLT1-e15a mRNAs in CTB (n=3 biologically independent experiments, mean + s.d.). hsiRNANTC – non-targeting hsiRNA control. ****P<0.0001, **P<0.01, *P<0.05, two-way ANOVA.

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