Supplementary Figure 5: Newborn pup numbers and weights from pregnant mice treated with hsiRNA. | Nature Biotechnology

Supplementary Figure 5: Newborn pup numbers and weights from pregnant mice treated with hsiRNA.

From: RNAi modulation of placental sFLT1 for the treatment of preeclampsia

Supplementary Figure 5

Pregnant CD1 mice were injected at day E14 and E15 with 2X20 mg/kg of hsiRNAsFLT1-2283, hsiRNANTC or PBS (IV, tail vein) and allowed to deliver pups on day E20. a-c). Newborn pups number and weights from mice injected with PBS or hsiRNAsFLT1 -2283 (n=9 biologically independent animals, boxes represent 25 to 75 percentiles and whiskers indicate minimal and maximal values, ns- non-significant, unpaired t test, two-tailed). d-e) Newborn pups number and weights from mice injected with PBS or hsiRNANTC (n=10 biologically independent animals, boxes represent 25 to 75 percentiles and whiskers indicate minimal and maximal values, ns- non-significant, unpaired t test, two-tailed).

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