Cytokine backpacks improve T-cell efficacy in the tumor microenvironment.
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T.S. is co-author on a patent application for constitutively active cytokine receptors for cell therapy.
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Shum, T., Heslop, H. A backpack revs up T-cell activity. Nat Biotechnol 36, 702–703 (2018). https://doi.org/10.1038/nbt.4215
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DOI: https://doi.org/10.1038/nbt.4215