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Portable gene expression guaranteed

Synthetic biology is made more reliable by borrowing ideas from systems and control theory.

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Figure 1: iFFL-stabilized promoters.

References

  1. Lee, S.K., Chou, H., Ham, T.S., Lee, T.S. & Keasling, J.D. Curr. Opin. Biotechnol. 19, 556–563 (2008).

    Article  CAS  Google Scholar 

  2. Ceroni, F., Algar, R., Stan, G.-B. & Ellis, T. Nat. Methods 12, 415–418 (2015).

    Article  CAS  Google Scholar 

  3. Segall-Shapiro, T.H., Sontag, E.D. & Voigt, C.A. Nat. Biotechnol. 36, 352–358 (2018).

    Article  CAS  Google Scholar 

  4. Grabherr, R., Nilsson, E., Striedner, G. & Bayer, K. Biotechnol. Bioeng. 77, 142–147 (2002).

    Article  CAS  Google Scholar 

  5. Arpino, J.A.J. et al. Microbiology 159, 1236–1253 (2013).

    Article  CAS  Google Scholar 

  6. Qi, L., Haurwitz, R.E., Shao, W., Doudna, J.A. & Arkin, A.P. Nat. Biotechnol. 30, 1002–1006 (2012).

    Article  CAS  Google Scholar 

  7. Ma, W., Trusina, A., El-Samad, H., Lim, W.A. & Tang, C. Cell 138, 760–773 (2009).

    Article  CAS  Google Scholar 

  8. Briat, C., Gupta, A. & Khammash, M. Cell Syst. 2, 15–26 (2016).

    Article  CAS  Google Scholar 

  9. Boch, J. et al. Science 326, 1509–1512 (2009).

    Article  CAS  Google Scholar 

  10. Del Vecchio, D., Ninfa, A.J. & Sontag, E.D. Mol. Syst. Biol. 4, 161 (2008).

    Article  Google Scholar 

Download references

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Correspondence to Guy-Bart Stan.

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Tomazou, M., Stan, GB. Portable gene expression guaranteed. Nat Biotechnol 36, 313–314 (2018). https://doi.org/10.1038/nbt.4119

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