Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6.

Gootenberg, J.S. et al. Science 10.1126/science.aaq0179 (2018).

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.

Chen, J.S. et al. Science 10.1126/science.aar6245 (2018).

The factors driving evolved herbicide resistance at a national scale.

Hicks, H.L. et al. Nature Ecol. Evol. 2, 529–536 (2018).

Skin electronics from scalable fabrication of an intrinsically stretchable transistor array.

Wang, S. et al. Nature 555, 83–88 (2018).

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.

Sockolosky, J.T. et al. Science 359, 1037–1042 (2018).

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.

Hu, J.H. et al. Nature 10.1038/nature26155 (2018).