Drug–device combination products are becoming increasingly prevalent, with many lasting years beyond the expiration date of primary and secondary patents on the drug itself.
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A.S.K.'s work is supported by the Laura and John Arnold Foundation and Harvard Program in Therapeutic Science, with additional support from the Engelberg Foundation. The authors are grateful to J.W. Nickerson, W.A. Kaplan, and A. Attaran for their feedback on developing this idea, as well as to J.J. Darrow and M.S. Sinha for their insights on earlier drafts.
The authors declare no competing financial interests.
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Beall, R., Kesselheim, A. Tertiary patenting on drug–device combination products in the United States. Nat Biotechnol 36, 142–145 (2018). https://doi.org/10.1038/nbt.4078
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