Ethical lessons from a tale of two genetically modified insects

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Figure 1: Annotated timeline of proposed A. aegypti field trial.
Figure 2: Annotated timeline of proposed field trial of the moth Plutella xylostella.

References

  1. 1

    Winskill, P. et al. PLoS Negl. Trop. Dis. 9, e0004156 (2015).

  2. 2

    Oye, K.A. et al. Science 345, 626–628 (2014).

  3. 3

    Resnik, D.B. Dev.World Bioeth. 14, 37–46 (2014).

  4. 4

    Caplan, A.L. et al. EMBO Rep. e201541337 (2015).

  5. 5

    National Academies of Sciences, Engineering, and Medicine. Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty, and Aligning Research with Public Values (The National Academies Press, Washington, DC, 2016).

  6. 6

    World Health Organization/Special Programme for Research and Training in Tropical Diseases and the Foundation for the National Institutes of Health. The Guidance Framework for Testing Genetically Modified Mosquitoes (WHO/TDR, Geneva, Switzerland, 2014) http://www.who.int/tdr/publications/year/2014/guide-fmrk-gm-mosquit/en/

  7. 7

    World Health Organization. Situation Report: Zika Virus, Microcephaly, Guillain-Barre Syndrome http://apps.who.int/iris/bitstream/10665/253604/1/zikasitrep20Jan17-eng.pdf?ua=1 (20 January 2017).

  8. 8

    Zalucki, M.P. et al. J. Econ. Entomol. 105, 1115–1129 (2012).

  9. 9

    Lopez, W. & Miller, J.R. J. Law Med. Ethics 30 Suppl, 135–138 (2002).

  10. 10

    Murphy, E.A., Post, G.B., Buckley, B.T., Lippincott, R.L. & Robson, M.G. Annu. Rev. Public Health 33, 209–224 (2012).

  11. 11

    Fernandez-Cornejo, J. et al. Pesticide Use in US Agriculture: 21 Selected Crops, 1960–2008 (USDA Economic Research Service, Washington, DC, 2014). https://www.ers.usda.gov/webdocs/publications/43854/46734_eib124.pdf?v=41830

  12. 12

    Rowe, G. & Frewer, L. Sci. Technol. Human Values 30, 251–290 (2005).

  13. 13

    Enserink, M. Science 330, 1030–1031 (2010).

  14. 14

    Subbaraman, N. Nat. Biotechnol. 29, 9–11 (2011).

  15. 15

    Florida Keys Mosquito Control District. Latest Information on the proposed Oxitec GM Mosquito Project. http://keysmosquito.org/oxitec-ox513a-trial/

  16. 16

    Shaw, D. Finger Lakes Times http://www.fltimes.com/news/experiment-station-defends-moth-trials/article_cae7ecf2-1ffd-11e5-9d1b-6b73566a4ed8.html (1 July 2015).

  17. 17

    US Department of Agriculture, Animal and Plant Health Inspection Service, Biotechnology Regulatory Services. National Environmental Policy Act Decision and Finding of No Significant Impact (USDA, Washington, DC, 2014). https://www.aphis.usda.gov/brs/aphisdocs/13_297102r_fonsi.pdf

  18. 18

    Greenberg, M. et al. Risk Anal. 35, 1959–1968 (2015).

  19. 19

    Van den Brink, P.J. et al. Mar. Freshw. Res. 67, 429–439 (2016).

  20. 20

    Adalja, A. et al. PLoS Curr. http://dx.doi.org/doi:10.1371/currents.outbreaks.1c39ec05a743d41ee39391ed0f2ed8d3 (2016).

  21. 21

    Hatfield, K. GEN: Genetic Engineering and Biotechnology News http://www.genengnews.com/gen-exclusives/historic-nantucket-weighs-use-of-disruptive-technology/77900678 (13 June 2016).

  22. 22

    Quinn, S.C. Am. J. Public Health 94, 918–922 (2004).

  23. 23

    Cohen, J. in Political Philosophy in the Twenty-First Century (eds. Cahn, S.M. & Talisse, R.B.) 217–235 (Westview Press, Boulder, CO, 2013).

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Correspondence to Carolyn P Neuhaus.

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Neuhaus, C., Caplan, A. Ethical lessons from a tale of two genetically modified insects. Nat Biotechnol 35, 713–716 (2017) doi:10.1038/nbt.3927

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