Supplementary Figure 4: Correlation between the gCSI and CTRP datasets. | Nature Biotechnology

Supplementary Figure 4: Correlation between the gCSI and CTRP datasets.

From: Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics

Supplementary Figure 4

(a) Spearman's correlation values between the two datasets based on conventional AUC (x-axis) or GRAOC (y-axis) for the nine drugs shared between the datasets. Mean increase in correlation and p-value of a t-test are reported. Note that gemcitabine (blue cross) is not included in the statistics because it was used for calibration. (b) Each pair of panels shows the AUC (left) or GRAOC (right) values calculated on the CTRP dataset versus the values on the gCSI dataset for all cell lines for each drug shared between the datasets. Each pair of plots is a different drug; Spearman's correlation is displayed at the top of each plot.

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