Research Highlights

    Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

    T-cell transfer therapy targeting mutant KRAS in cancer

    Tran, E. et al. N. Engl. J. Med. 375, 2255–2262 (2016)

    Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

    Dewey, F.E. et al. Science 354, aaf6814 (2016)

    Perturb-Seq: dissecting molecular circuits with scalable single-cell RNA profiling of pooled genetic screens

    Dixit, A. et al. Cell 167, 1853–1866.e17 (2016)

    A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response

    Adamson, B. et al. Cell 167, 1867–1882.e21 (2016)

    Dissecting immune circuits by linking CRISPR-pooled screens with single-cell RNA-seq

    Jaitin, D.A. et al. Cell 167, 1883–1896.e15 (2016)

    Rights and permissions

    Reprints and Permissions

    About this article

    Verify currency and authenticity via CrossMark

    Cite this article

    Research Highlights. Nat Biotechnol 35, 127 (2017).

    Download citation