Supplementary Figure 3: Effect distributions of experimental mutation scans | Nature Biotechnology

Supplementary Figure 3: Effect distributions of experimental mutation scans

From: Mutation effects predicted from sequence co-variation

Supplementary Figure 3

The analyzed experimental datasets show considerable differences in the overall shape of their effect distributions. Many of the experiments are biased towards large fractions of neutral or deleterious variants, or have bimodal effect distributions biased towards either end of the effect scale but with little resolution of intermediate effects (here measured by the skewness and normality of the distributions (Online Methods); plots are ordered from negative to positive skew). Summary statistics can also be found in Supplementary Table 4.

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