Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Defining synonymous codon compression schemes by genome recoding

Wang, K. et al. Nature 539, 59–64 (2016)

GenomeCRISPR—a database for high-throughput CRISPR/Cas9 screens

Rauscher, B., Heigwer, F., Breinig, M., Winter, J. & Boutros, M. Nucl. Acids Res. 10.1093/nar/gkw997 (2016)

In vivo continuous evolution of genes and pathways in yeast

Crook, N. et al. Nat. Commun. 7, 13051 (2016)

Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery

Mao, A.S. et al. Nat. Mater. 10.1038/nmat4781 (2016)

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

Sapparapu, G. et al. Nature 10.1038/nature20564 (2016)