Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Precision medicine for autoimmune disease

An antigen-specific cell therapy for autoimmune disease avoids compromising immunity as a whole.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Figure 1: Applying chimeric autoantigen receptors to treat autoimmunity.

Kim Caesar/Nature Publishing Group

References

  1. 1

    Ellebrecht, C.T. et al. Science 353, 179–184 (2016).

    CAS  Article  Google Scholar 

  2. 2

    Bach, J.-F. N. Engl. J. Med. 347, 911–920 (2002).

    Article  Google Scholar 

  3. 3

    Chatenoud, L. Curr. Opin. Pharmacol. 23, 92–97 (2015).

    CAS  Article  Google Scholar 

  4. 4

    Hammers, C.M. et al. J. Invest. Dermatol. 135, 742–749 (2015).

    CAS  Article  Google Scholar 

  5. 5

    Phillips, W.D. & Vincent, A. F1000 Res. 5, 1513 (2016).

    Article  Google Scholar 

  6. 6

    Luo, J. et al. J. Neurosci. 29, 13898–13908 (2009).

    CAS  Article  Google Scholar 

  7. 7

    Ambrosi, A., Sonesson, S.E. & Wahren-Herlenius, M. Exp. Cell Res. 325, 2–9 (2014).

    CAS  Article  Google Scholar 

  8. 8

    Gleicher, N. & Elkayam, U. Autoimmun. Rev. 12, 1039–1045 (2013).

    CAS  Article  Google Scholar 

  9. 9

    Skog, A., Lagnefeldt, L., Conner, P., Wahren-Herlenius, M. & Sonesson, S.E. Acta Obstet. Gynecol. Scand. 95, 98–105 (2016).

    CAS  Article  Google Scholar 

  10. 10

    Serreze, D.V. et al. J. Exp. Med. 184, 2049–2053 (1996).

    CAS  Article  Google Scholar 

  11. 11

    Pescovitz, M.D. et al. N. Engl. J. Med. 361, 2143–2152 (2009).

    CAS  Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Lucienne Chatenoud.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Chatenoud, L. Precision medicine for autoimmune disease. Nat Biotechnol 34, 930–932 (2016). https://doi.org/10.1038/nbt.3670

Download citation

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing