Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Automated design of DNA origami

A top-down computational method enables fabrication of DNA objects in any shape.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Fully automated, top-down design procedure to create arbitrary DNA nanostructures.

References

  1. Veneziano, R. et al. Science 352, 1534 (2016).

    Article  CAS  Google Scholar 

  2. Rothemund, P.W.K. Nature 440, 297–302 (2006).

    Article  CAS  Google Scholar 

  3. Linko, V. & Dietz, H. Curr. Opin. Biotechnol. 24, 555–561 (2013).

    Article  CAS  Google Scholar 

  4. Jones, M.R., Seeman, N.C. & Mirkin, C.A. Science 347, 1260901 (2015).

    Article  Google Scholar 

  5. Castro, C.E. et al. Nat. Methods 8, 221–229 (2011).

    Article  CAS  Google Scholar 

  6. Pan, K. et al. Nat. Commun. 5, 5578 (2014).

    Article  CAS  Google Scholar 

  7. Benson, E. et al. Nature 523, 441–444 (2015).

    Article  CAS  Google Scholar 

  8. Benson, E. et al. Angew. Chem. Int. Ed. http://dx.doi.org/10.1002/anie.201602446 (2016).

  9. Surana, S., Shenoy, A.R. & Krishnan, Y. Nat. Nanotechnol. 10, 741–747 (2015).

    Article  CAS  Google Scholar 

  10. Linko, V., Ora, A. & Kostiainen, M.A. Trends Biotechnol. 33, 586–594 (2015).

    Article  CAS  Google Scholar 

  11. Sun, W. et al. Science 346, 1258361 (2014).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Veikko Linko or Mauri A Kostiainen.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Linko, V., Kostiainen, M. Automated design of DNA origami. Nat Biotechnol 34, 826–827 (2016). https://doi.org/10.1038/nbt.3647

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt.3647

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing