Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Whole organism lineage tracing by combinatorial and cumulative genome editing

McKenna, A. et al. Science doi:10.1126/science.aaf7907 (2016)

Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array

Fuller, C. et al. PNAS 113, 5233–5238 (2016)

Biomimetic proteolipid vesicles for targeting inflamed tissues

Molinaro, R. et al. Nat. Mater. doi:10.1038/nmat4644 (2016)

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

Kranz, L.M. et al. Nature 534, 396–401 (2016)

Signaling from maize organ primordia via FASCIATED EAR3 regulates stem cell proliferation and yield traits

Je, B. et al. Nat. Genet. doi:10.1038/ng.3567 (2016)

Culturing of 'unculturable' human microbiota reveals novel taxa and extensive sporulation

Browne, H.P. et al. Nature 533, 543–546 (2016)