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Safer conditioning for blood stem cell transplants

An antibody-based conditioning agent may open the way to wider application of gene therapy with hematopoietic stem cells.

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Figure 1: A comparison of conventional allogeneic HSCT with autologous HSCT using genetically corrected or uncorrected stem cells.

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Correspondence to Alessandro Aiuti or Luigi Naldini.

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Aiuti, A., Naldini, L. Safer conditioning for blood stem cell transplants. Nat Biotechnol 34, 721–723 (2016).

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