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Generation of knockout mice by Cpf1-mediated gene targeting

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Figure 1: Generation of Cpf1-mediated Trp53 mutant mice.


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This study was supported by the Ministry of Science, ICT and Future Planning (MSIP) through the National Research Foundation of Korea (NRF) (2013R1A1A1009962, 2014M3A9D5A01073836, 2015R1A1A1A05001483). This work was also supported by a grant (2016-649) from the Asan Institute for Life Sciences, Asan Medical Center, Seoul, Korea. We appreciate the technical assistance from the Genomics Core Laboratory of Asan Institute for Life Sciences.

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Correspondence to Sang-Wook Lee, Myeong Sup Lee, In-Jeoung Baek or Young Hoon Sung.

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Kim, Y., Cheong, SA., Lee, J. et al. Generation of knockout mice by Cpf1-mediated gene targeting. Nat Biotechnol 34, 808–810 (2016).

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