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Targeted mutagenesis in mice by electroporation of Cpf1 ribonucleoproteins

Nature Biotechnology volume 34, pages 807808 (2016) | Download Citation

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Acknowledgements

We thank Ji-hyun Ju for the help with the next-generation sequencing, and the members of the Genome Engineering Lab for helpful discussions and comments. This work was supported by the Institute for Basic Science (IBS-R021-D1 to J.-S.K.).

Author information

Author notes

    • Junho K Hur
    •  & Kyoungmi Kim

    These authors contributed equally to this work.

Affiliations

  1. Center for Genome Engineering, Institute for Basic Science, Seoul, Republic of Korea.

    • Junho K Hur
    • , Kyoungmi Kim
    • , Kyung Wook Been
    • , Gayoung Baek
    • , Sunghyeok Ye
    • , Junseok W Hur
    • , Seuk-Min Ryu
    • , Youn Su Lee
    •  & Jin-Soo Kim
  2. Department of Chemistry, Seoul National University, Seoul, Republic of Korea.

    • Kyung Wook Been
    • , Seuk-Min Ryu
    •  & Jin-Soo Kim
  3. Basic Science, IBS School, Korea University of Science and Technology, Seoul, Republic of Korea.

    • Sunghyeok Ye
  4. Department of Neurosurgery, Korea University College of Medicine, Seoul, Republic of Korea.

    • Junseok W Hur
  5. ToolGen, Seoul, Republic of Korea.

    • Youn Su Lee

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Competing interests

J.-S.K., J.K.H., and K.M.K. have filed a patent application based on this work.

Corresponding author

Correspondence to Jin-Soo Kim.

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    Supplementary Figures 1–8, Supplementary Tables 1–4, Supplementary Note and Supplementary Methods

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DOI

https://doi.org/10.1038/nbt.3596

Editor's note: This article has been peer reviewed.

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