Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Correspondence
  • Published:

Regulate genome-edited products, not genome editing itself

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout


  1. Carlson, D.F. et al. Nat. Biotechnol. 34, 479–481 (2016).

    Article  CAS  Google Scholar 

  2. Medugorac, I. et al. PLoS One 7, e39477 (2012).

    Article  CAS  Google Scholar 

  3. Wiedemar, N. et al. PLoS One 9, e93435 (2014).

    Article  Google Scholar 

  4. Rothammer, S. et al. Genet. Sel. Evol. 46, 44 (2014).

    Article  Google Scholar 

  5. Carroll, D. Annu. Rev. Biochem. 83, 409–439 (2014).

    Article  CAS  Google Scholar 

  6. Kim, H. & Kim, J.S. Nat. Rev. Genet. 15, 321–334 (2014).

    Article  CAS  Google Scholar 

  7. Doudna, J.A. & Charpentier, E. Science 346, 1258096 (2014).

    Article  Google Scholar 

  8. Tan, W. et al. Proc. Natl. Acad. Sci. USA 110, 16526–16531 (2013).

    Article  CAS  Google Scholar 

  9. Palmgren, M.G. et al. Trends Plant Sci. 20, 155–164 (2015).

    Article  CAS  Google Scholar 

  10. Office of Science and Technology Policy (OSTP). Fed. Regist. 51, 23301 (1986).

  11. Food and Drug Administration (FDA). Guidance for Industry (187): Regulation of genetically engineered animals containing heritable recombinant DNA constructs (2009).

  12. Food and Drug Administration (FDA). Genetically engineered animals general Q&A. (2015).

  13. Daetwyler, H.D. et al. Nat. Genet. 46, 858–865 (2014).

    Article  CAS  Google Scholar 

  14. Tebas, P. et al. N. Engl. J. Med. 370, 901–910 (2014).

    Article  CAS  Google Scholar 

  15. Ledford, H. Nature 527, 417–418 (2015).

    Article  CAS  Google Scholar 

  16. Van Eenennaam, A.L. & Muir, W.M. Nat. Biotechnol. 29, 706–710 (2011).

    Article  CAS  Google Scholar 

  17. Office of Science and Technology Policy (OSTP). Fed. Regist. 57, 6753 (1992).

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Dana Carroll.

Ethics declarations

Competing interests

D.C. and J.F.T. are on the Scientific Advisory Board of Recombinetics, Inc., which has undertaken the molecular introgression of the Pc allele described here. A.L.V.E. is a co-Project Director on a USDA grant (2015-67015-23316 “Improvement of dairy cattle well-being by genetic dehorning”) to achieve this goal. D.F.V. is a founder of Calyxt, which applies genome editing to plants. J.S. declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Carroll, D., Van Eenennaam, A., Taylor, J. et al. Regulate genome-edited products, not genome editing itself. Nat Biotechnol 34, 477–479 (2016).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research