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Serotonin neurons in a dish

A method for generating serotonin raphe neurons in vitro will aid the study of genetic variants and drugs that modulate serotonin activity.

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Figure 1: Specification of serotonin neurons in vivo and in vitro.

References

  1. Eley, T.C. et al. Mol. Psychiatry 9, 908–915 (2004).

    Article  CAS  Google Scholar 

  2. Waider, J., Araragi, N., Gutknecht, L. & Lesch, K.P. Psychoneuroendocrinology 36, 393–405 (2011).

    Article  CAS  Google Scholar 

  3. Lu, J. et al. Nat. Biotechnol. 34, 89–94 (2016).

    Article  CAS  Google Scholar 

  4. Kiyasova, V. & Gaspar, P. Eur. J. Neurosci. 34, 1553–1562 (2011).

    Article  Google Scholar 

  5. Deneris, E.S. & Wyler, S.C. Nat. Neurosci. 15, 519–527 (2012).

    Article  CAS  Google Scholar 

  6. Okaty, B.W. et al. Neuron 88, 774–791 (2015).

    Article  CAS  Google Scholar 

  7. Fernandez, S.P. et al. Brain Struct. Funct. 10.1007/s00429-015-1142-4 (25 November 2015).

  8. Dias, J.M., Alekseenko, Z., Applequist, J.M. & Ericson, J. Neuron 84, 927–939 (2014).

    Article  CAS  Google Scholar 

  9. Maury, Y. et al. Nat. Biotechnol. 33, 89–96 (2015).

    Article  CAS  Google Scholar 

  10. Xu, Z. et al. Mol. Psychiatry 10.1038/mp.2015.101 (28 July 2015).

  11. Vadodaria, K.C. et al. Mol. Psychiatry 10.1038/mp.2015.161 (27 October 2015).

Download references

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Correspondence to Patricia Gaspar.

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Gaspar, P., Nedelec, S. Serotonin neurons in a dish. Nat Biotechnol 34, 41–42 (2016). https://doi.org/10.1038/nbt.3455

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