Correspondence | Published:

Increased bioavailable vitamin B6 in field-grown transgenic cassava for dietary sufficiency

Nature Biotechnology volume 33, pages 10291032 (2015) | Download Citation

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    & Molecules 15, 442–459 (2010).

  2. 2.

    et al. Emerg. Infect. Dis. 19, 1374–1384 (2013).

  3. 3.

    & Cell. Mol. Life Sci. 62, 1671–1681 (2005).

  4. 4.

    & Free Radic. Biol. Med. 36, 423–428 (2004).

  5. 5.

    Science 336, 144–146 (2012).

  6. 6.

    et al. PLoS One 8, e66419 (2013).

  7. 7.

    et al. PLoS One 8, e54113 (2013).

  8. 8.

    et al. Annu. Rev. Plant Biol. 62, 251–272 (2011).

  9. 9.

    et al. Plant Cell 24, 395–414 (2012).

  10. 10.

    et al. Proc. Natl. Acad. Sci. USA 102, 13687–13692 (2005).

  11. 11.

    et al. Front. Plant Sci. 4, 143 (2013).

  12. 12.

    et al. Plant J. 66, 414–432 (2011).

  13. 13.

    & Plant Biotechnol. J. 7, 673–681 (2009).

  14. 14.

    & Annu. Rev. Plant Physiol. Plant Mol. Biol. 51, 167–194 (2000).

  15. 15.

    Annu. Rev. Nutr. 18, 277–296 (1998).

  16. 16.

    et al. Plant J. 75, 40–52 (2013).

  17. 17.

    , & Am. J. Physiol. Cell Physiol. 285, C1219–C1225 (2003).

  18. 18.

    , & J. Nutr. 123, 85–89 (1993).

  19. 19.

    , , & J. Nutr. 134, 842–846 (2004).

  20. 20.

    , & J. Nutr. Sci. Vitaminol. (Tokyo) 34, 179–187 (1988).

  21. 21.

    Food Nutr. Res. 56, 5809 (2012).

  22. 22.

    et al. Front. Plant Sci. 4, 526 (2013).

Download references

Acknowledgements

We acknowledge support from ETH Zurich, the University of Geneva, the Swiss National Science Foundation (project 31003A_140911) and the Earmarked Fund for the China Agriculture Research System (CARS-12-shzp). We thank S. Klarer and I. Zurkirchen (ETH Zurich) for special care of the cassava plants. We are grateful to M. de Meyer (University of Geneva) and M. Bosma (University of Utrecht) for assistance with the microbial assays and the Caco-2 cell assay, respectively.

Author information

Affiliations

  1. Department of Biology, ETH Zurich, Zurich, Switzerland.

    • Kuan-Te Li
    • , Nathalie Mangel
    • , Wilhelm Gruissem
    •  & Hervé Vanderschuren
  2. Department of Botany and Plant Biology, University of Geneva, Geneva, Switzerland.

    • Michael Moulin
    •  & Teresa B Fitzpatrick
  3. Department of Medical Genetics, University Medical Center, Utrecht, the Netherlands.

    • Monique Albersen
    •  & Nanda M Verhoeven-Duif
  4. SIBS-ETH Shanghai Center for Cassava Biotechnology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

    • Qiuxiang Ma
    • , Peng Zhang
    •  & Wilhelm Gruissem
  5. AgroBioChem Department, Gembloux Agro-Bio Tech, University of Liège, Liège, Belgium.

    • Hervé Vanderschuren

Authors

  1. Search for Kuan-Te Li in:

  2. Search for Michael Moulin in:

  3. Search for Nathalie Mangel in:

  4. Search for Monique Albersen in:

  5. Search for Nanda M Verhoeven-Duif in:

  6. Search for Qiuxiang Ma in:

  7. Search for Peng Zhang in:

  8. Search for Teresa B Fitzpatrick in:

  9. Search for Wilhelm Gruissem in:

  10. Search for Hervé Vanderschuren in:

Competing interests

The authors declare no competing financial interests.

Corresponding authors

Correspondence to Teresa B Fitzpatrick or Wilhelm Gruissem or Hervé Vanderschuren.

Supplementary information

PDF files

  1. 1.

    Supplementary Figures, Tables and Text

    Supplementary Figures 1–8, Supplementary Materials and Methods and Supplementary Tables 1–5

About this article

Publication history

Published

DOI

https://doi.org/10.1038/nbt.3318

Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing