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Health ROI as a measure of misalignment of biomedical needs and resources

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Figure 1: Health ROI for overstudied and understudied conditions (see Supplementary Table 5 for the top 50 over- and understudied conditions in 2011).
Figure 2: Disease-specific health ROIs.

Change history

  • 07 August 2015

    In the version of this article initially published, a footnote and boldface type were omitted from Table 1. The column heading 'Correlation and P-values' should have read 'Correlation'. The footnote should have read “Bold: significant correlation coefficients, P < 0.01.” In the body of the table, P-values were present in all cells, but these should have been omitted and bold face should have been used to indicate significant correlation coefficients. The errors have been corrected in the HTML and PDF versions of the article.


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We are grateful to R. Kumar and H. Madsen for helpful comments on earlier versions of the manuscript. This work was supported by US National Institutes of Health grants 1P50MH094267 and U01HL108634-01 (A.R.), GlaxoSmithKline funds (L.Y., Y.L., S.G.) and the University of North Carolina at Charlotte Faculty Research Grant (L.Y.).

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Correspondence to Lixia Yao or Andrey Rzhetsky.

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S.G. is an employee of GlaxoSmithKline.

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Supplementary Data; Supplementary Tables 1–5 Supplementary Figure 1 (PDF 692 kb)

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Yao, L., Li, Y., Ghosh, S. et al. Health ROI as a measure of misalignment of biomedical needs and resources. Nat Biotechnol 33, 807–811 (2015).

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