This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Exploring static and dynamic relationships between burden of disease and research funding in the United States
Health Research Policy and Systems Open Access 03 June 2022
-
The relationship between government research funding and the cancer burden in South Korea: implications for prioritising health research
Health Research Policy and Systems Open Access 23 December 2019
-
Evaluating global and local sequence alignment methods for comparing patient medical records
BMC Medical Informatics and Decision Making Open Access 19 December 2019
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Change history
07 August 2015
In the version of this article initially published, a footnote and boldface type were omitted from Table 1. The column heading 'Correlation and P-values' should have read 'Correlation'. The footnote should have read “Bold: significant correlation coefficients, P < 0.01.” In the body of the table, P-values were present in all cells, but these should have been omitted and bold face should have been used to indicate significant correlation coefficients. The errors have been corrected in the HTML and PDF versions of the article.
References
Merton, R.C. Bell J. Econ. 4, 141–183 (1973).
Black, F. & Scholes, M. J. Polit. Econ. 81, 637–654 (1973).
Gross, C.P., Anderson, G.F. & Powe, N.R. N. Engl. J. Med. 340, 1881–1887 (1999).
Gillum, L.A. et al. PLoS ONE 6, e16837 (2011).
Sampat, B.N., Buterbaugh, K. & Perl, M. Milbank Q. 91, 163–185 (2013).
Vanderelst, D. & Speybroeck, N. J. Informetrics 7, 240–247 (2013).
Evans, J.A., Shim, J.-M. & Ioannidis, J.P. PLoS ONE 9, e90147 (2014).
Murray, C. Bull. World Health Organ. 72, 429–445 (1994).
Reiss, J. & Kitcher, P. THEORIA 24, 263–282 (2010).
Kleinbaum, D., Kupper, L., Nizam, A. & Rosenberg, E. Applied regression analysis and other multivariable methods (Cengage Learning, 2013).
Vanderelst, D. & Speybroeck, N. PLoS Negl. Trop. Dis. 4, e576 (2010).
Acknowledgements
We are grateful to R. Kumar and H. Madsen for helpful comments on earlier versions of the manuscript. This work was supported by US National Institutes of Health grants 1P50MH094267 and U01HL108634-01 (A.R.), GlaxoSmithKline funds (L.Y., Y.L., S.G.) and the University of North Carolina at Charlotte Faculty Research Grant (L.Y.).
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Competing interests
S.G. is an employee of GlaxoSmithKline.
Supplementary information
Supplementary Data
Supplementary Data; Supplementary Tables 1–5 Supplementary Figure 1 (PDF 692 kb)
Rights and permissions
About this article
Cite this article
Yao, L., Li, Y., Ghosh, S. et al. Health ROI as a measure of misalignment of biomedical needs and resources. Nat Biotechnol 33, 807–811 (2015). https://doi.org/10.1038/nbt.3276
Published:
Issue Date:
DOI: https://doi.org/10.1038/nbt.3276
This article is cited by
-
Exploring static and dynamic relationships between burden of disease and research funding in the United States
Health Research Policy and Systems (2022)
-
Measuring the impact of health research data in terms of data citations by scientific publications
Scientometrics (2022)
-
The relationship between government research funding and the cancer burden in South Korea: implications for prioritising health research
Health Research Policy and Systems (2019)
-
Evaluating global and local sequence alignment methods for comparing patient medical records
BMC Medical Informatics and Decision Making (2019)