Nature Biotechnology asks selected members of the international community to comment on the ethical issues raised by the prospect of CRISPR-Cas9 engineering of the human germline.

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Author information


  1. Editas Medicine, Cambridge, Massachusetts, USA.

    • Katrine S Bosley
  2. Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA.

    • Michael Botchan
  3. Department of Medical Humanities, University Medical Center, Utrecht, the Netherlands.

    • Annelien L Bredenoord
  4. Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, USA.

    • Dana Carroll
  5. School of Law, and Department of Medical History and Bioethics, University of Wisconsin School of Medicine & Public Health, Madison, Wisconsin, USA.

    • R Alta Charo
  6. Department of Regulation in Infection Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

    • Emmanuelle Charpentier
  7. Acorda Therapeutics, Ardsley, New York, USA.

    • Ron Cohen
  8. Innovative Genomics Initiative, Berkeley, California, USA.

    • Jacob Corn
  9. Department of Molecular & Cell Biology and Chemistry, University of California, Berkeley, Berkeley, California, USA.

    • Jennifer Doudna
  10. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA.

    • Guoping Feng
  11. Stanford Law School, Stanford, California, USA.

    • Henry T Greely
  12. Department of Human Genetics, McGill University, Montreal, Quebec, Canada.

    • Rosario Isasi
  13. Kunming Biomed International and National Engineering Research Center of Biomedicine and Animal Science, Kunming, China.

    • Weihzi Ji
  14. Center for Genome Engineering, Institute for Basic Science and Department of Chemistry, Seoul National University, Seoul, Korea.

    • Jin-Soo Kim
  15. Department of Human Genetics, McGill University, Montreal, Quebec, Canada.

    • Bartha Knoppers
  16. Sangamo Biosciences, Richmond, California, USA.

    • Edward Lanphier
  17. Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

    • Jinsong Li
  18. The Francis Crick Institute, London, UK.

    • Robin Lovell-Badge
  19. Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA.

    • G Steven Martin
  20. University of Pennsylvania, Philadelphia, Pennsylvania, USA.

    • Jonathan Moreno
  21. San Raffaele Telethon Institute for Gene Therapy, Milan, Italy.

    • Luigi Naldini
  22. Department of Anatomy and Neuroscience, University of Melbourne, Melbourne, Australia.

    • Martin Pera
  23. Department of Biology and Biochemistry, University of Bath, Bath, UK.

    • Anthony CF Perry
  24. J. Craig Venter Institute in La Jolla, California, USA.

    • J Craig Venter
  25. Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

    • Feng Zhang
  26. State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.

    • Qi Zhou


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