Commentary | Published:

The digital phenotype

Nature Biotechnology volume 33, pages 462463 (2015) | Download Citation

In the coming years, patient phenotypes captured to enhance health and wellness will extend to human interactions with digital technology.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    The Extended Phenotype: the Gene as the Unit of Selection. (Oxford: Oxford University Press; 1982).

  2. 2.

    , & N. Engl. J. Med. 360, 2153–2155 (2009).

  3. 3.

    & J. Affect. Disord. 148, 411–412 (2013).

  4. 4.

    , , & Nat. Biotechnol. 29, 411–414 (2011).

  5. 5.

    , , & J. Neuroeng. Rehabil. 11, 36 (2014).

Download references


J.S.B and J.B.H are supported by the National Human Genome Research Institute BD2K grant 1U54HG007963-01.

Author information


  1. Sachin H. Jain is at Caremore Health System, Cerritos, California, USA

    • Sachin H Jain
  2. Brian W. Powers, Jared B. Hawkins and John S. Brownstein are at Harvard Medical School, Boston, Massachusetts, USA

    • Brian W Powers
    • , Jared B Hawkins
    •  & John S Brownstein
  3. Sachin H. Jain is at Boston-Virginia Medical Center, Boston, Massachusetts, USA, and Merck and Co., Inc., Boston, Massachusetts, USA

    • Sachin H Jain
  4. John S. Brownstein and Jared B. Hawkins is at Children's Hospital Boston, Boston, Massachusetts, USA.

    • Jared B Hawkins
    •  & John S Brownstein


  1. Search for Sachin H Jain in:

  2. Search for Brian W Powers in:

  3. Search for Jared B Hawkins in:

  4. Search for John S Brownstein in:

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Sachin H Jain.

About this article

Publication history



Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing