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Quality score compression improves genotyping accuracy

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Figure 1: Compressive quality scores using the Quartz algorithm.
Figure 2: Scaled ROC curves of genotyping accuracy.

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Acknowledgements

We thank L. Cowen and N. Daniels for helpful discussions and comments. Y.W.Y. gratefully acknowledges support from the Fannie and John Hertz Foundation. D.Y., J.P. and B.B. are partially supported by US National Institutes of Health grant GM108348.

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Correspondence to Bonnie Berger.

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Supplementary information

Supplementary Figures and Text

Supplementary Figures 1–12, Supplementary Tables 1–6 and Supplementary Methods (PDF 889 kb)

Supplementary Code

Source code for the Quartz software described and used in the manuscript (ZIP 23 kb)

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Yu, Y., Yorukoglu, D., Peng, J. et al. Quality score compression improves genotyping accuracy. Nat Biotechnol 33, 240–243 (2015). https://doi.org/10.1038/nbt.3170

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