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Biopharmaceutical benchmarks 2014

Monoclonal antibodies continue their march on the markets, optimized so-called biobetter versions of existing biologics are also gaining ground, but the rate of biosimilar approvals has seen a dramatic slowdown in recent years.

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Figure 1: Approvals by region and by date.
Figure 2: mAbs approved within the indicated periods, expressed as a percentage of total biopharmaceutical product approvals within the same period.
Figure 3: Product approvals, cumulative (1982–2014) and for the current period (2010–July 2014) in the context of product class.
Figure 4
Figure 5: Expression systems used to manufacture biopharmaceutical products.


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Corresponding author

Correspondence to Gary Walsh.

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The author declares no competing financial interests.

Supplementary information

Supplementary Table 1

New traditional-type biotech product* approvals 2010-2014. (PDF 161 kb)

Supplementary Table 2

Stem cell products in phase 3 clinical trials (PDF 50 kb)

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Walsh, G. Biopharmaceutical benchmarks 2014. Nat Biotechnol 32, 992–1000 (2014).

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