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Wheat rescued from fungal disease

Knockout of all six alleles of a gene in the large wheat genome confers resistance to powdery mildew.

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Figure 1: SSNs slice into big DNA.


  1. Voytas, D.F. Annu. Rev. Plant Biol. 64, 327–350 (2013).

    Article  CAS  Google Scholar 

  2. Wang, Y. et al. Nat. Biotechnol. doi:10.1038/nbt.2969 (27 June 2014).

  3. Bockus, W.W. Compendium of Wheat Diseases and Pests (APS Press, 2010).

    Google Scholar 

  4. Consonni, C. et al. Nat. Genet. 38, 716–720 (2006).

    Article  CAS  Google Scholar 

  5. Piffanelli, P. et al. Nature 430, 887–891 (2004).

    Article  CAS  Google Scholar 

  6. Bai, Y. et al. Mol. Plant Microbe Interact. 21, 30–39 (2008).

    Article  CAS  Google Scholar 

  7. Collins, N.C. et al. Nature 425, 973–977 (2003).

    Article  CAS  Google Scholar 

  8. International Wheat Genome Sequencing Consortium (IWGSC). Science 345, 1251788 (2014).

  9. Ledford, H. Nature 500, 389–390 (2013).

    Article  CAS  Google Scholar 

  10. Baltes, N.J., Gil-Humanes, J., Cermak, T., Atkins, P.A. & Voytas, D.F. Plant Cell 26, 151–163 (2014).

    Article  CAS  Google Scholar 

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Correspondence to Daniel F. Voytas.

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Competing interests

D.F.V. is an inventor on a TALEN patent and consults for a company that uses TALENS for plant genome engineering.

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Gil-Humanes, J., Voytas, D. Wheat rescued from fungal disease. Nat Biotechnol 32, 886–887 (2014).

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