The reliability of scientific research is under scrutiny. A recently convened working group proposes cultural adjustments to incentivize better research practices.
This is a preview of subscription content
Subscribe to Journal
Get full journal access for 1 year
only $8.25 per issue
All prices are NET prices.
VAT will be added later in the checkout.
Tax calculation will be finalised during checkout.
Get time limited or full article access on ReadCube.
All prices are NET prices.
Johnson, G. New truths that only one can see. New York Times 21 January (2014).
Greenwald, A.G. Psychol. Bull. 82, 1–20 (1975).
Sedlmeier, P. & Gigerenzer, G. Psychol. Bull. 105, 309–316 (1989).
Edwards, A.W. Biol. Rev. Camb. Philos. Soc. 61, 295–312 (1986).
Martinson, B.C., Anderson, M.S. & de Vries, R. Nature 435, 737–738 (2005).
Timmer, J. Ars Technica http://arstechnica.com/science/2007/04/how-doubling-the-nihs-budget-created-a-funding-crisis/ (20 April 2007).
Brunner, D., Balci, F. & Ludvig, E.A. Behav. Processes 89, 187–195 (2012).
Ioannidis, J.P. et al. Nat. Genet. 29, 306–309 (2001).
Hirschhorn, J.N. N. Engl. J. Med. 360, 1699–1701 (2009).
Pocock, S.J., Hughes, M.D. & Lee, R.J. N. Engl. J. Med. 317, 426–432 (1987).
Schulz, K.F. et al. Br. Med. J. 340, c332 (2010).
Kilkenny, C. et al. PLoS Biol. 8, e1000412 (2010).
Welch, V. et al. PLoS Med. 9, e1001333 (2012).
von Elm, E. et al. PLoS Med. 4, e296 (2007).
Editorial. Nat. Methods 10, 367 (2013).
Editorial. Nat. Biotechnol. 31, 943 (2013).
Wagenmakers, E.J. & Forstmann, B.U. Cortex 51, 105–106 (2014).
Menalled, L. et al. A Field Guide to Working with Mouse Models of Huntington's Disease (The Jackson Laboratory, 2014).
Button, K.S. et al. Nat. Rev. Neurosci. 14, 365–376 (2013).
Ioannidis, J.P., Hozo, I. & Djulbegovic, B. J. Clin. Epidemiol. 66, 903–910 (2013).
Liang, F. et al. J. Am. Stat. Assoc. 103, 410–423 (2008).
Kerr, N.L. Pers. Soc. Psychol. Rev. 2, 196–217 (1998).
The World Medical Association. J. Am. Med. Assoc. 310, 2191–2194 (2013).
Ioannidis, J.P. Perspect. Psychol. Sci. 7, 645–654 (2012).
S.N. and R.B. are employees of CHDI Management, Inc., which provides advisory services to CHDI Foundation and other nonprofit organizations that support Huntington's disease research. D.B. is employed by PsychoGenics, Inc., which conducts research through fee-for-service agreements for CHDI. J.F. and D.L. receive research funding from CHDI. All authors received reimbursement of travel costs for attendance at the working group cited. M.M., W.J.B., G.L., M.L., E.-J.W. and K.T. have now signed consulting agreements with CHDI to work on the independent standing committee cited.
About this article
Cite this article
Munafò, M., Noble, S., Browne, W. et al. Scientific rigor and the art of motorcycle maintenance. Nat Biotechnol 32, 871–873 (2014). https://doi.org/10.1038/nbt.3004
Systemic problems require systemic solutions: the need for coordination and cooperation to improve research quality
BMC Research Notes (2022)
Nature Human Behaviour (2017)
Statistics in Biosciences (2017)