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A patent perspective on US stem cell research

What are the implications of recent US Supreme Court decisions on the patent eligibility of stem cells?

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References

  1. Armstrong, L. et al. Stem Cells 30, 2–9 (2012).

    CAS  Article  Google Scholar 

  2. Schwartz, S.D. et al. Lancet 379, 713–720 (2012).

    CAS  Article  Google Scholar 

  3. Tachibana, M. et al. Cell 153, 1228–1238 (2013).

    CAS  Article  Google Scholar 

  4. Burrone, E. Patents at the core: the biotech business (2006). http://www.wipo.int/sme/en/documents/patents_biotech_fulltext.html

  5. Bergman, K. & Graff, G.D. Nat. Biotechnol. 25, 419–424 (2007).

    CAS  Article  Google Scholar 

  6. Mayo v. Prometheus, 566 US 132 (2012).

  7. Parker v. Flook, 437 US 584 (1978).

  8. Hirshfeld, A.H. 2012 Interim Procedure for Subject Matter Eligibility Analysis of Process Claims Involving Laws of Nature (USPTO memorandum, 3 July 2012). http://www.uspto.gov/patents/law/exam/2012_interim_guidance.pdf

    Google Scholar 

  9. Rogers, E.J. J. Pat. Trademark Off. Soc. 19, 93 (2011).

    Google Scholar 

  10. Ass'n v. USPTO, 702 F. Supp. 2d 181 (S.D.N.Y., 2010).

  11. Ass'n v. USPTO, 653 F. 3d 1329 (2011).

  12. Ass'n v. USPTO, 689 F. 3d 1303 (2012).

  13. Ass'n v. Myriad, 569 US 12–398 (2013).

  14. Hirshfeld, A.H. Supreme Court Decision in Association for Molecular Pathology v. Myriad Genetics, Inc. (USPTO memorandum, 13 June 2013). http://www.uspto.gov/patents/law/exam/myriad_20130613.pdf

  15. Hirshfeld, A.H. 2014 Procedure for Subject Matter Eligibility Analysis of Claims Reciting or Involving Laws of Nature/Natural Principles, Natural Phenomena, and/or Natural Products (USPTO memorandum, 4 March, 2014). http://www.uspto.gov/patents/law/exam/myriad-mayo_guidance.pdf

  16. Zuhn, D.L. USPTO Holds Forum on Subject Matter Eligibility—Part I (Patent Docs, 12 May 2014). http://www.patentdocs.org/2014/05/uspto-holds-forum-on-subject-matter-eligibility-part-i.html

  17. Zuhn, D.L. USPTO Holds Forum on Subject Matter Eligibility—Part III (Patent Docs, 15 May 2014). http://www.patentdocs.org/2014/05/uspto-holds-forum-on-subject-matter-eligibility-part-iii.html

  18. Offit, K. et al. J. Clin. Oncol. 31, 2743–2748 (2013).

    Article  Google Scholar 

  19. Rosenfeld, J.A. & Mason, C.E. Genome Med. 5, 27 (2013).

    CAS  Article  Google Scholar 

  20. Thomson, J.A. US Patent No. 6,200,806 (2001).

  21. Section 27 of Leahy-Smith America Invents Act. Public Law 112-29 (2011).

  22. In re Bilski, 545 F.3d 943 (2008).

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Acknowledgements

We thank N. Yi-Chen Su for insights into and comments on this article.

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Correspondence to Albert Wai-Kit Chan, Alice Yuen-Ting Wong or Hon-Man Lee.

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The authors declare competing financial interests: details are available in the online version of the paper (doi:10.1038/nbt.2945).

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Chan, AK., Wong, AT. & Lee, HM. A patent perspective on US stem cell research. Nat Biotechnol 32, 633–637 (2014). https://doi.org/10.1038/nbt.2945

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