The goal of characterizing solid-tumor genomes with nothing more than a blood sample is now within reach.
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References
Pantel, K. & Alix-Panabieres, C. Cancer Res. 73, 6384–6388 (2013).
Lohr, J.G. et al. Nat. Biotechnol. 32, 479–484 (2014).
Bettegowda, C. et al. Sci. Transl. Med. 6, 224ra224 (2014).
Im, H. et al. Nat. Biotechnol. 32, 488–493 (2014).
Lawrence, M.S. et al. Nature 505, 495–501 (2014).
Gerlinger, M. et al. N. Engl. J. Med. 366, 883–892 (2012).
Hou, Y. et al. Cell 148, 873–885 (2012).
Pantel, K., Brakenhoff, R.H. & Brandt, B. Nat. Rev. Cancer 8, 329–340 (2008).
Wan, L., Pantel, K. & Kang, Y. Nat. Med. 19, 1450–1464 (2013).
Heitzer, E. et al. Cancer Res. 73, 2965–2975 (2013).
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Speicher, M., Pantel, K. Tumor signatures in the blood. Nat Biotechnol 32, 441–443 (2014). https://doi.org/10.1038/nbt.2897
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DOI: https://doi.org/10.1038/nbt.2897
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