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Gene editing at CRISPR speed

Nature Biotechnology volume 32, pages 309–312 (2014)Cite this article

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Ease of use, economy and speed of targeting DNA has propelled the CRISPR-Cas system into the spotlight. Now, despite numerous gaps in our knowledge, commercial entities are looking for a piece of the action. Monya Baker reports.

But with the technology so young and posing so many questions, it remains to be seen whether CRISPR-Cas will supersede its predecessors, such as transcription activator–like effector nucleases (TALENs) or zinc finger nucleases (ZFNs), especially when the latter have decades of research behind them and are now showing promising clinical results (see p. 315).

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Gene editing at CRISPR speed. Nat Biotechnol 32, 309–312 (2014). https://doi.org/10.1038/nbt.2863

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