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E. coli network upgrade

Combining yeast two-hybrid data with mass-spectrometry and structural data provides a detailed view of the E. coli interactome.

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Figure 1: The path toward a detailed, high-resolution E. coli interactome map starts by combining binary protein-protein interaction data from yeast two-hybrid analysis and data from affinity purification–MS5,6,7.

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Correspondence to Ulrich Stelzl.

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The author declares no competing financial interests.

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Stelzl, U. E. coli network upgrade. Nat Biotechnol 32, 241–243 (2014). https://doi.org/10.1038/nbt.2848

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