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Cytokine-driven beta-cell production in vivo

Transient treatment of diabetic mice with two cytokines induces acinar-to-beta-cell conversion to an extent sufficient to durably restore normoglycemia.

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Figure 1: Schematic of cytokine-induced conversion of pancreatic acinar cells into new beta-like cells.

Katie Vicari


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Correspondence to Mark A Magnuson.

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The authors declare no competing financial interests.

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Worchel, H., Magnuson, M. Cytokine-driven beta-cell production in vivo. Nat Biotechnol 32, 63–64 (2014).

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