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Cytokine-driven beta-cell production in vivo

Nature Biotechnology volume 32, pages 63–64 (2014)Cite this article

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Transient treatment of diabetic mice with two cytokines induces acinar-to-beta-cell conversion to an extent sufficient to durably restore normoglycemia.

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Figure 1: Schematic of cytokine-induced conversion of pancreatic acinar cells into new beta-like cells.

Katie Vicari

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Authors and Affiliations

  1. and in the Department of Cell and Developmental Biology, Hannah N. Worchel and Mark A. Magnuson are at the Center for Stem Cell Biology, Vanderbilt University, Nashville, Tennessee, USA, Vanderbilt University, Nashville, Tennessee, USA,

    Hannah N Worchel & Mark A Magnuson

  2. Mark A. Magnuson is also in the Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.,

    Mark A Magnuson

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  1. Hannah N Worchel
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  2. Mark A Magnuson
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Correspondence to Mark A Magnuson.

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The authors declare no competing financial interests.

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Worchel, H., Magnuson, M. Cytokine-driven beta-cell production in vivo. Nat Biotechnol 32, 63–64 (2014). https://doi.org/10.1038/nbt.2788

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