Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Plasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission

Bobenchik, A.M. et al. Proc. Natl. Acad. Sci. USA 110, 18262–18267 (2013)

Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing

Guo, H. et al. Genome Res. doi:10.1101/gr.161679.113 (31 October 2013)

Structural basis for the modular recognition of single-stranded RNA by PPR proteins

Yin, P. et al. Nature doi:10.1038/nature12651 (27 October 2013)

Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure

Ho, Y. et al. Cell 155, 540–551 (2013)

Genetic identification of a neural circuit that suppresses appetite

Carter, M.E. et al. Nature 503, 111–114 (2013)