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Next-generation sequencing in the clinic

Pools of cell lines carrying a variety of known mutations are used to validate the performance of a cancer diagnostic test based on next-generation sequencing.

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Figure 1: Clinical sequencing test protocol and validation.

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Correspondence to Jason Y Park.

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Park, J., Kricka, L. & Fortina, P. Next-generation sequencing in the clinic. Nat Biotechnol 31, 990–992 (2013). https://doi.org/10.1038/nbt.2743

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