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Precompetitive consortia in biomedicine—how are we doing?

Nature Biotechnology volume 31, pages 979–985 (2013)Cite this article

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Too few precompetitive consortia are being formed to mitigate lost opportunities and deliver on other potential mutual gains for public and private stakeholders in drug development.

What are consortia good for?

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References

  1. FDA. The beginnings: laboratory and animal studies. Information for Consumers (Drugs) http://www.fda.gov/Drugs/ResourcesForYou/Consumers/ucm143475.htm (2011).

  2. Miller, G. Necessity driving leery pharma “open.” FiercebiotechIThttp://www.fiercebiotechit.com/story/necessity-driving-leery-pharma-open/2011-04-04(2013).

  3. Pollack, A. Drug makers join efforts in research. New York Times (20 September 2012).

    Google Scholar 

  4. Cutcher-Gershenfeld, J. & Lawson, C. Valuing the commons: a fundamental challenge across complex systems. (NSF, Washington, DC, 2010).

  5. Bunin, B.A. & Ekins, S. Drug Discov. Today 16, 643–645 (2011).

    Article  Google Scholar 

  6. Lessl, M., Bryans, J.S., Richards, D. & Asadullah, K. Nat. Rev. Drug Discov. 10, 241–242 (2011).

    CAS  Article  Google Scholar 

  7. DiMasi, J.A., Hansen, R.W. & Grabowski, H.G. J. Health Econ. 22, 151–185 (2003).

    Article  Google Scholar 

  8. Toronto International Data Release Workshop Authors. Nature 461, 168–170 (2009).

  9. Hunter, J. & Stephens, S. Nat. Rev. Drug Discov. 9, 87–88 (2010).

    CAS  Article  Google Scholar 

  10. Munos, B. Clin. Pharmacol. Ther. 87, 534–536 (2010).

    CAS  Article  Google Scholar 

  11. Waitz, I., Townsend, J., Cutcher-Gershenfeld, J., Greitzer, E. & Kerrebrock, J. Aviation and the environment: a national vision statement, goals and recommended actions. http://web.mit.edu/aeroastro/partner/reports/congrept_aviation_envirn.pdf (FAA/NASA, Washington, DC, 2004).

  12. Masum, H. & Harris, R. Open source for neglected diseases: magic bullet or mirage? (Results for Development Institute, Washington, DC, 2011).

  13. Cutcher-Gershenfeld, J., Mittleman, B., Dickherber, A., Mayrand-Chung, S. & Franks, A. Stakeholder alignment in the Biomarkers Consortium. (NSF-VOSS EAGER 0956472, Washington, DC, 2012).

  14. Woelfle, M., Olliaro, P. & Todd, M.H. Nat. Chem. 3, 745–748 (2011).

    CAS  Article  Google Scholar 

  15. Cutcher-Gershenfeld, J., Barrett, B. & Lawson, C. Building the internal organization to support lateral alignment: a case study of the Office of Environment and Energy, Federal Aviation Administration http://ssrn.com/abstract=2345248 (MIT, Cambridge, Massachusetts, 2005).

  16. Walton, R. & McKersie, R. A Behavioral Theory of Labor Negotiations. (McGraw Hill, New York, 1965).

    Google Scholar 

  17. DiMasi, J.A., Hansen, R.W. & Grabowski, H.G. The price of innovation: new estimates of drug development costs. J. Health Econ. 22, 151–185 (2003).

    Article  Google Scholar 

  18. Wagner, J.A. et al. Clin. Pharmacol. Ther. 86, 619–625 (2009).

    CAS  Article  Google Scholar 

Download references

Acknowledgements

We appreciate support for this research provided under NSF-VOSS EAGER 0956472, “Stakeholder Alignment in Socio-Technical Systems.”

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Affiliations

  1. Barbara Mittleman was at the US National Institutes of Health, Bethesda, Maryland, USA and is presently at Nodality, South San Francisco, California, USA.

    Barbara Mittleman

  2. Garry Neil is at Johnson & Johnson, New Brunswick, New Jersey, USA.

    Garry Neil

  3. Joel Cutcher-Gershenfeld is at the University of Illinois at Urbana-Champaign, Illinois, USA.

    Joel Cutcher-Gershenfeld

Authors
  1. Barbara Mittleman
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  2. Garry Neil
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  3. Joel Cutcher-Gershenfeld
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Corresponding author

Correspondence to Barbara Mittleman.

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The authors declare no competing financial interests.

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Mittleman, B., Neil, G. & Cutcher-Gershenfeld, J. Precompetitive consortia in biomedicine—how are we doing?. Nat Biotechnol 31, 979–985 (2013). https://doi.org/10.1038/nbt.2731

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