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At the frontiers of lung fibrosis therapy

Despite recent failures, a flurry of activity in biotech and pharma is raising hopes that an effective drug for this fatal lung disease is on the way. Ken Garber investigates.

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Figure 1: In IPF, the normal wound healing response goes fatally wrong, as resident fibroblasts become collagen-secreting myofibroblasts that cause continuous scar formation in the lung.

Katie Vicari

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At the frontiers of lung fibrosis therapy. Nat Biotechnol 31, 781–783 (2013). https://doi.org/10.1038/nbt.2687

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