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All charged up about implanted biomaterials

Nature Biotechnology volume 31, pages 507–509 (2013)Cite this article

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A zwitterionic polymer hinders the foreign-body response that leads to fibrotic encapsulation of implants.

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Figure 1: Temporal representation of the host response leading to encapsulation of an implanted material.

Marina Corral Spence

References

  1. Anderson, J.M., Rodriguez, A. & Chang, D.T. Semin. Immunol. 20, 86–100 (2008).

    Article  CAS  Google Scholar 

  2. Zhang, L., Cao, Z., Bai, T., Carr, L., Ella-Menye, J.-R., Irvin, C., Ratner, B.D. & Jiang, S. Nat. Biotechnol. 31, 553–556 (2013).

    Article  CAS  Google Scholar 

  3. Tian, W. & Kyriakides, T.R. Biomed. Mater. 4, 015010 (2009).

    Article  Google Scholar 

  4. Holt, D. & Grainger, D.W. Host-implant response. in An Introduction to Biomaterials, 2nd edn. (ed., Hollinger, J.O.) 63–95 (CRC Press, Boca Raton, FL, 2011).

    Google Scholar 

  5. Wu, P. & Grainger, D.W. Biomaterials 27, 2450–2467 (2006).

    Article  CAS  Google Scholar 

  6. Ward, W.K., Wood, M.D., Casey, H.M., Quinn, M.J. & Federiuk, I.F. Diabetes Technol. Ther. 6, 137–145 (2004).

    Article  CAS  Google Scholar 

  7. Ishihara, K. 2012. Phospholipid polymers. in Encyclopedia of Polymer Science and Technology (John Wiley & Sons, 2012).

    Google Scholar 

  8. Williams, D.F. Biomaterials 29, 2941–2953 (2008).

    Article  CAS  Google Scholar 

  9. Zhang, Z. et al. J. Biomater. Sci. Polym. Ed. 20, 1845–1859 (2009).

    Article  CAS  Google Scholar 

  10. Smith, R.S. et al. Sci. Transl. Med. 4, 153ra132 (2012)

    PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. David W. Grainger is in the Department of Pharmaceutics and Pharmaceutical Chemistry, and the Department of Bioengineering, University of Utah, Salt Lake City, Utah, USA.,

    David W Grainger

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  1. David W Grainger
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Correspondence to David W Grainger.

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Grainger, D. All charged up about implanted biomaterials. Nat Biotechnol 31, 507–509 (2013). https://doi.org/10.1038/nbt.2600

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