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Compartmentalizing metabolic pathways in organelles

Nature Biotechnology volume 31, pages 320–321 (2013)Cite this article

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The entire metabolic pathway for producing a biofuel is confined within a yeast organelle to increase yield over the endogenous pathway split between two compartments.

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Figure 1: Eukaryotic organelles offer multiple environments distinct from the cytosol that may be attractive for engineering metabolism.

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Authors and Affiliations

  1. William C. DeLoache and John E. Dueber are at the Energy Biosciences Building, University of California, Berkeley, California, USA.,

    William C DeLoache & John E Dueber

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  1. William C DeLoache
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  2. John E Dueber
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Correspondence to John E Dueber.

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The authors declare no competing financial interests.

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DeLoache, W., Dueber, J. Compartmentalizing metabolic pathways in organelles. Nat Biotechnol 31, 320–321 (2013). https://doi.org/10.1038/nbt.2549

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