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RNA guides genome engineering

Nature Biotechnology volume 31, pages 208209 (2013) | Download Citation

The Cas9 endonuclease is reprogrammed by RNAs for site-specific modification of eukaryotic and microbial genomes.

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Author information

Affiliations

  1. Claudio Mussolino and Toni Cathomen are at the Laboratory of Cell and Gene Therapy, Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany.

    • Claudio Mussolino
    •  & Toni Cathomen

Authors

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Toni Cathomen.

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DOI

https://doi.org/10.1038/nbt.2527

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