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Analyzing the association of SCNA boundaries with replication timing

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Figure 1: Only the overly simplistic 'independent' background model, whereby SCNA ends are chosen independently, neglecting long-range replication time correlation (black bars), yields an estimate for ends to reside in the same timing domain, which differs from the observed (white bars) fraction in a biologically meaningful way.

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Correspondence to Sven Bilke.

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Bilke, S., Gindin, Y. Analyzing the association of SCNA boundaries with replication timing. Nat Biotechnol 30, 1043–1045 (2012). https://doi.org/10.1038/nbt.2415

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