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T-cell therapy at the threshold

Despite impressive clinical activity in B-cell lymphoma and melanoma, questions remain about the immunobiology of adoptive T-cell therapies.

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Correspondence to Carl June, Steven A Rosenberg, Michel Sadelain or Jeffrey S Weber.

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June, C., Rosenberg, S., Sadelain, M. et al. T-cell therapy at the threshold. Nat Biotechnol 30, 611–614 (2012).

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