New lysine methyltransferase drug targets in cancer

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Recent preclinical studies suggest that inhibitors of histone methyltransferases represent promising drug candidates for cancer therapy.

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Figure 1: Protein lysine methylation.

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Acknowledgements

We thank the Deutsche Krebshilfe (Nr. 107898) for funding of our work on histone methyltransferases.

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Correspondence to Manfred Jung.

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The authors declare no competing financial interests.

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Wagner, T., Jung, M. New lysine methyltransferase drug targets in cancer. Nat Biotechnol 30, 622–623 (2012) doi:10.1038/nbt.2300

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